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Derivatization in Analytical Chemistry
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Derivatization is one of the most widely used sample pretreatment techniques in Analytical Chemistry and Chemical Analysis. Reagent-based or reagent-less schemes offer improved detectability of target compounds, modification of the chromatographic properties and/or the stabilization of sensitive compounds until analysis. Either coupled with separation techniques or as a “stand alone” analytical procedure, derivatization offers endless possibilities in all aspects of analytical applications.
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Keywords
- 2-naphthalenethiol
- 96-microwell spectrophotometric assay
- A/P ratio
- acetazolamide
- acetonitrile-related adducts
- acetylenic lipids
- amino acids
- Analytical Chemistry
- Biogenic Amines
- blood plasma
- BSTFA
- carbonic anhydrase
- charge-transfer reaction
- chemical warfare agents
- Chemistry
- chiral metabolomics
- chloranilic acid
- Clams
- creatine
- creatinine
- d-amino acids
- derivatisation
- derivatization
- dimethyl labeling
- double and triple bond localization
- enantiomer separation
- enhancement
- esterification
- fluorescence detection
- fluorosurfactant-modified gold nanoparticles
- GC-MS
- GC–MS
- glutamine
- high-performance liquid chromatography
- high-resolution mass spectrometry
- high-throughput pharmaceutical analysis
- homocysteine
- homocysteine thiolactone
- HPLC
- HPLC-UV/Vis
- human serum albumin
- in-source derivatization
- Inhibition
- linseed oil
- low-molecular-weight thiols
- Lycium barbarum L.
- Mass Spectrometry
- Mathematics & science
- Methylation
- monobromobimane
- nerve agents
- Novichoks
- o-phthalaldehyde
- P/S ratio
- pentafluorobenzyl bromide
- pentafluoropropionic anhydride
- pharmacokinetics
- pigment
- quantification
- Reduction
- Reference, information & interdisciplinary subjects
- Research & information: general
- rice water
- sarin
- silylation
- sodium borohydride
- Stability
- sulforaphane
- Taurine
- TMS
- toluene
- Tyrosine kinase inhibitors
- ureide
- Validation
- zone fluidics
- α-lipoic acid
- ∑D
Links
DOI: 10.3390/books978-3-0365-4255-3Editions