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Oxidative Stress and Inflammation
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In the biochemical reactions that take place within all living beings, species called free radicals are generated. Denham Harman, in his study on the origin and evolution of life (Harman, 2001), proposes that these species are amongst the causes of the origin of life on our planet. Oxygen is a molecule that provides the primary source of energy in aerobic organisms and therefore is key to the development and evolution of life. On the one hand, it gives rise to life; on the other, due to its ability to form different free radicals, it is capable of damaging essential structures for development. To combat these radicals, our biological systems have developed antioxidant defenses. However, when the balance between free radicals and antioxidant defenses is broken in favor of the former, a phenomenon called oxidative stress occurs, which ends up damaging molecules such as DNA, proteins, carbohydrates, and lipids (Sies, 1983) (Halliwell and Gutteridge, 1985). This phenomenon is implicated both in the development of diseases and in their progression. In addition, inflammation phenomena are also involved in most pathologies, which, although they are essential for tissue repair and immunity, turn against our bodies when they become excessively active. For these reasons, in this special edition we showcase an extensive knowledge of the effects of oxidative stress and inflammation both in diseases such as aging, or for its role in health.
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Keywords
- 5-lipoxigenase
- acute respiratory distress syndrome
- adiponectin
- Aging
- Air Pollution
- anti-inflammation
- anti-inflammatory diets
- anti-inflammatory response
- antiplatelet
- aspirin
- Astragalus mongholicus Bunge
- biomarker
- Calcium
- caloric restriction
- Cardiovascular Disease
- Cardiovascular Diseases
- CHOP
- chronic inflammation
- corneal damage
- cyclophosphamide
- cytokine
- Cytokines
- danazol
- data analysis
- Dementia
- diabetic kidney disease
- dimethyl sulfoxide
- diospyrin
- docetaxel
- doxorubicin
- DPH
- DPPP
- dry eye syndrome
- endogenous antioxidants
- Exercise
- experimental model
- Fas
- functional groups
- gender
- Health
- hydroperoxides
- hyperimmunized milk
- Inflammation
- inflammatory models
- inflammatory response
- intestinal permeability
- leukotriene B4
- lipopolysaccharide
- low grade chronic inflammation
- lung inflammation
- lysophospholipids
- Macrophages
- medicine
- Medicine: General Issues
- Mediterranean Diet
- membrane erythrocyte
- microbiota
- Microglia
- Mild Cognitive Impairment
- n-3 PUFAs
- n/a
- neuroinflammation
- Nitric Oxide
- Nutrition
- Oriental diet
- oxidative balance
- Oxidative Stress
- oxygen reactive species
- p38 MAPK
- paclitaxel
- particulate matter
- Plasma
- Polyphenols
- porcine liver decomposition product
- precision–recall
- prostaglandins
- Public health & preventive medicine
- redox imbalance
- Soot
- tear lipidome
- telomerase
- Telomere
- Therapy
- TMA
- white adipose tissue
- zileuton
Links
DOI: 10.3390/books978-3-0365-6024-3Editions