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Oxidative Stress in Brain Function
Waldo Cerpa (editor)
2024
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The different cellular mechanisms that govern complex brain functions are regulated through intrinsic (genetic) or external (environmental) factors. One of the most critical regulatory axes at the cellular level is established around the cellular capacities that counteract the oxidative stress emerging in different pathophysiological contexts. At the brain level, this control is essential due to the limited capacity of neurons in forming new cells. Therefore, brain cells cope very efficiently with oxidative stress, and their functions are only altered when these cellular strategies are overwhelmed. This reprint contains original research and review articles on the regulation of cellular processes where antioxidant defenses are essential for maintaining the normal functioning of brain cells, including different cellular signaling mechanisms and their dysfunction.
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Keywords
- 3CAI
- allopregnanolone
- amlodipine
- Amyotrophic lateral sclerosis
- Antioxidants
- Apoptosis
- astrocyte
- Autophagy
- Brain
- c-Abl
- Calcium
- CAT
- Catalase
- Cell Death
- Cognition
- Electroencephalography
- Endoplasmic Reticulum Stress
- free radicals
- glial cultures
- Glutathione
- GPx1
- GSH
- GSSG
- Heavy metals
- Hippocampus
- inflammation and immunity
- KO mice
- kynurenic acid
- L-type voltage-gated calcium channel
- Lipid Peroxidation
- MDA
- Microglia
- Mitochondria
- mitochondria unfolded protein response
- mitochondrial calcium
- mitochondrial fusion
- mitofusin 2
- N-acetylcysteine
- NAC
- NCLX
- neurodegeneration
- Neurodegenerative Diseases
- neuroinflammation
- Neuronal Death
- Neuroprotection
- neurosteroids
- Nitric Oxide
- nitrosative stress
- NLRP3 inflammasome
- NOx
- Nox4
- Nrf2
- Oxidative Stress
- oxygen homeostasis
- proteostasis
- rat
- Reactive Oxygen Species
- rotenone
- Schizophrenia
- seizure
- Sleep
- Sleep deprivation
- SOD
- Stress
- superoxide dismutase
- thema EDItEUR::M Medicine and Nursing
- thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology
- Therapeutics
- TMCB
- Traumatic Brain Injury
- Zinc
Links
DOI: 10.3390/books978-3-7258-1150-2Editions