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3D Printing of Pharmaceuticals and Drug Delivery Devices

3D Printing of Pharmaceuticals and Drug Delivery Devices

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The 3D printing (3DP) process was patented in 1986; however, only in the last decade has it begun to be used for medical applications, as well as in the fields of prosthetics, bio-fabrication, and pharmaceutical printing. 3DP or additive manufacturing (AM) is a family of technologies that implement layer-by-layer processes in order to fabricate physical models based on a computer aided design (CAD) model. 3D printing permits the fabrication of high degrees of complexity with great reproducibility in a fast and cost-effective fashion. 3DP technology offers a new paradigm for the direct manufacture of individual dosage forms and has the potential to allow for variations in size and geometry as well as control dose and release behavior. Furthermore, the low cost and ease of use of 3DP systems means that the possibility of manufacturing medicines and medical devices at the point of dispensing or at the point of use could become a reality. 3DP thus offers the perfect innovative manufacturing route to address the critical capability gap that hinders the widespread exploitation of personalized medicines for molecules that are currently not easy to deliver. This Special Issue will address new developments in the area of 3D printing and bioprinting for drug delivery applications, covering the recent advantages and future directions of additive manufacturing for pharmaceutical products.

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Keywords

  • 3D bio-inks
  • 3D bio-printing
  • 3D bioprinting
  • 3D printed drug products
  • 3D printed oral dosage forms
  • 3D printing
  • acetaminophen
  • additive manufacturing
  • amorphous solid dispersion
  • anti-infective devices
  • antioxidant materials
  • aspirin (acetylsalicylic acid)
  • beads
  • Biodegradable
  • Biofilm formation
  • bioprinting
  • chemical modification
  • chronotherapeutic delivery
  • complex structures
  • computer-aided design (CAD)
  • computer-aided design (CAD) design
  • controlled release
  • cyclodextrin
  • digital light processing technology
  • digital pharmacy
  • dissolution kinetics
  • Drug delivery
  • Drug development
  • drug release
  • extrusion
  • extrusion-based 3D printing
  • feature size
  • filament extrusion
  • fixed dose combination
  • fixed-dose combinations
  • floating systems
  • FMD
  • fused deposition modeling
  • fused deposition modeling (FDM)
  • fused deposition modeling 3D printing
  • fused deposition modelling
  • fused filament fabrication
  • fused layer modeling
  • gastric floating
  • gastro-retentive floating system
  • Geometry
  • gums
  • high API load
  • high-precision targeting
  • hospital pharmacy
  • hot-melt extrusion
  • implantable devices
  • implantable scaffold
  • Inkjet printing
  • lignin
  • Materials
  • Mechanical properties
  • medicine
  • micro-implant
  • micro-swimmer
  • micromedicine
  • microneedle
  • modified drug release
  • modified release
  • MTT assay
  • multiple units
  • multiple-layer dosage forms
  • neural networks
  • on-demand manufacturing
  • optimization
  • oral dosages
  • oral powder
  • orodisperible films
  • orodispersible discs
  • orodispersible film
  • paracetamol (acetaminophen)
  • patient-specific
  • pectin
  • pediatric
  • pelvic organ prolapse
  • personalised medicines
  • personalized medicine
  • personalized medicines
  • personalized pharmaceuticals
  • pharmaceutical quality control
  • pharmaceuticals
  • pharmaceutics
  • pharmacoprinting
  • photopolymerization
  • polylactic acid
  • polymeric ink
  • Polymers
  • poor solubility
  • prediction
  • pregabalin
  • pressure-assisted microsyringe (PAM)
  • printlets
  • Process
  • processing parameters
  • prolonged drug delivery
  • propolis
  • pseudo-bone
  • pulsatile release
  • release profile
  • resolution
  • semisolid extrusion 3D printing
  • solid dosage forms
  • spheroids
  • stencil printing
  • stereolithography
  • stress urinary incontinence
  • structural design
  • subcutaneous
  • sustained drug release tablets
  • Tablets
  • Telemedicine
  • theophylline
  • three dimensional printing
  • three-dimensional printing
  • vaginal meshes
  • vascularization
  • vat polymerisation
  • warfarin
  • wound dressing
  • wound-healing

Links

DOI: 10.3390/books978-3-03936-424-4

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