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Diet and Microbiome in Health and Aging
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Diet plays a fundamental role in shaping the composition and metabolic activity of the gut microbiota and, thus, it could determine the interrelationship between the gut microbiome and the host. The colon is the part of the human body that is most densely populated, containing bacteria, archaea, viruses, and some unicellular eukaryotes that have co-evolved with humans in a commensal way. The gut microbiota plays a crucial role in the maintenance of normal host physiology. The rapid development of next-generation sequencing (NGS) methods for DNA sequencing in the last decade has facilitated in-depth study of gut microbiome composition and function. These methods have contributed to providing evidence regarding the relevance of the intestinal microbiota for host health as well as the basis for putative dietary interventions aimed at counteracting microbiota dysbiosis. Understanding the complex and dynamic interaction between dietary exposures and gut microbiota can help to elucidate their potential role in different pathologies and to guide future strategies for the prevention and treatment of diseases. Age-related changes in the gut microbiome are also associated with physiological changes in the gastrointestinal tract as well as in dietary patterns, with a concomitant decline in the normal function of the immune system that may contribute to increased risk of infection and frailty. More studies are needed to better understand how the microbiota shifts with different environmental factors and how they are associated with dietary changes.
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Keywords
- (poly)phenol
- acacia fiber
- aetiology
- Aged
- allergic rhinitis
- Alzheimer’s disease
- antihyperglycemia
- Asthma
- Autism Spectrum Disorder
- Bacteroides
- Bifidobacterium
- Biology, Life Sciences
- blueberries
- Children
- Chronic Disease
- Clinician
- coffee
- Cognitive decline
- comorbidities
- Cultural Studies
- Diet
- dietary indices
- dietary intake
- dietary patterns
- elderly
- Enterococcus
- faecal microbial transplant
- Faecalibacterium prausnitzii
- Food & society
- Gut Microbiota
- Healthy ageing
- human study
- IgA
- Immune system
- implantation failure
- in vitro
- Infants
- Infertility
- Inflammation
- inulin fiber
- Lactobacillus paracasei
- Lactobacillus salivarius
- Mathematics & science
- Mediterranean Diet
- Metagenomics
- microbiome
- microbiota
- microbiota–gut–brain axis
- mineral absorption
- n/a
- neuroinflammation
- Orienteering
- Oxidative Stress
- Polyphenols
- Prebiotic
- Prebiotics
- probiotic
- Probiotics
- Reference, information & interdisciplinary subjects
- repetitive abortion
- Research & information: general
- Society & culture: general
- Society & Social Sciences
- Staphylococcus
- synbiotics
- TGF-β
- type 2 diabetes mellitus
- vaginal microbiome
- VEGF
- weight gain
- Western diet
Links
DOI: 10.3390/books978-3-0365-5364-1Editions