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Fatty Acids and Cardiometabolic Health
Jason Wu and Matti Marklund
2019
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The impact of fat intake on hypercholesterolemia and related atherosclerotic cardiovascular diseases has been studied for decades. However, the current evidence base suggests that fatty acids also influences cardiometabolic diseases through other mechanisms including effects on glucose metabolism, body fat distribution, blood pressure, inflammation, and heart rate. Furthermore, studies evaluating single fatty acids have challenged the simplistic view of shared health effects within fatty acid groups categorized by degree of saturation. In addition, investigations of endogenous fatty acid metabolism, including genetic studies of fatty acid metabolizing enzymes, and the identification of novel metabolically derived fatty acids have further increased the complexity of fatty acids’ health impacts. This Special Issue aims to include original research and up-to-date reviews on genetic and dietary modulation of fatty acids, and the role and function of dietary and metabolically derived fatty acids in cardiometabolic health.
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Keywords
- Adipose Tissue
- alternatively activated macrophages
- antioxidant
- arachidonic acid
- blood lipids
- Blood pressure
- Body Weight
- CAD
- cardiometabolic disease
- Cardiovascular Disease
- CHD
- Children
- cholesterol ester
- CKD
- Cohort study
- conjugated fatty acids
- COPD
- coronary artery disease
- CYP450 eicosanoids
- desaturase
- Diet
- docosapentaenoic acid
- EEQs
- EETs
- Epidemiology
- erucic acid
- FADS
- Fat
- fatty acid
- Fibrosis
- fish
- Fish Oil
- furan fatty acids
- Genome-wide association study (GWAS)
- genotype
- hemodynamics
- Human
- Inflammation
- Insulin sensitivity
- ischemic heart disease
- klotho
- linoleic acid
- Lipid Metabolism
- long-chain triglyceride
- Low-fat diet
- Mediterranean Diet
- medium-chain triglyceride
- metabolic disease
- n-3 fatty acids
- n-3 PUFA
- n-6 fatty acids
- Obesity
- omega 3
- Omega-3
- omega-3 PUFA
- omega-6 PUFA
- perivascular adipose tissue
- prospective cohort study
- PUFA
- Seafood
- statins
- substitution models
- thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
- Type 2 cytokines
- type 2 diabetes mellitus
- unsaturated fat
Links
DOI: 10.3390/books978-3-03897-891-6Editions
