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Human milk is uniquely tailored to meet infants’ specific nutritional requirements. However, it is more than just “milk”. This dynamic and bioactive fluid allows mother–infant signalling over lactation, guiding the infant in the developmental and physiological processes. It exerts protection and life-long biological effects, playing a crucial role in promoting healthy growth and optimal cognitive development. The latest scientific advances have provided insight into different components of human milk and their dynamic changes over time. However, the complexity of human milk composition and the synergistic mechanisms responsible for its beneficial health effects have not yet been unravelled. Filling this knowledge gap will shed light on the biology of the developing infant and will contribute to the optimization of infant feeding, particularly that of the most vulnerable infants. Greater understanding of human milk will also help in elucidating the best strategies for its storage and handling. The increasing knowledge on human milk’s bioactive compounds together with the rapidly-advancing technological achievements will greatly enhance their use as prophylactic or therapeutic agents. The current Special Issue aims to welcome original works and literature reviews further exploring the complexity of human milk composition, the mechanisms underlying the beneficial effects associated with breastfeeding, and the factors and determinants involved in lactation, including its promotion and support.
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Keywords
- 2?-fucosyllactose (2?FL)
- 3?-sialyllactose (3?SL)
- ?-linolenic acid
- ?-tocopherol
- adipokines
- amino acids
- antenatal
- antioxidant capacity
- Antioxidants
- arachidonic acid (ARA)
- bile salt stimulated lipase
- bioactive factors
- Body Composition
- breast milk
- Breastfeeding
- breastfeeding difficulties
- breastfeeding support
- Calcium
- carbohydrate
- carotenoids
- celiac disease
- choline
- Clinical Trial
- colostrum
- Copper
- Country
- Cytokines
- dietary assessment
- dietary intake
- digestive tract
- disialyllacto-N-tetraose (DSLNT)
- Docosahexaenoic acid
- docosahexaenoic acid (DHA)
- donor human milk
- donor milk
- duration of lactation
- early breastfeeding cessation
- eicosapentaenoic acid
- eicosapentaenoic acid (EPA)
- endogenous peptide
- expressing
- Fat
- Fatty acids
- Flow injection analysis
- flu vaccine
- food frequency questionnaire
- glycoprotein
- Growth
- Growth factors
- high pressure processing
- high-performance liquid chromatography (HPLC)
- Hormones
- human milk
- human milk benefits
- human milk fat
- human milk fortification
- human milk oligosaccharides (HMO)
- immune-active proteins
- inadequate intake
- Infant
- infant formula
- Infants
- iodine
- Iron
- lactating women
- Lactation
- lactational stage
- lactose
- late preterm
- LC-MS
- lewis
- lipid metabolites
- lipidomics
- Lipids
- macronutrients
- magnesium
- mammary gland
- maternal diet
- maternal immunoglobulins
- milk banking
- Milk Fat Globule Membrane
- milk group
- milk therapy
- Mothers
- mothers’ own milk
- multiple source method
- n-9 fatty acid
- n/a
- Neonate
- nervonic acid
- Nutrition
- nutritional status
- Omega-3 fatty acids
- Online
- passive immunization
- pasteurization
- phosphocholine
- phospholipids
- phosphorus
- Potassium
- Pregnancy
- prematurity
- preterm
- preterm infant
- promotion of breastfeeding
- prospective study
- protease inhibitors
- Proteases
- protective factors
- Protein
- pumping
- retinol
- secretor
- selenium
- sodium
- Storage
- supplementation
- targeted metabolomics
- Term
- term infant
- term infants
- thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
- undernourishment
- video instruction
- vitamin D deficiency
- Zinc