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Oxidative Stress in Diabetic Retinopathy
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The combination of an increasing prevalence of diabetes and the aging of populations enables the appearance of a greater number of associated complications such as diabetic retinopathy. Diabetic retinopathy is the leading cause of preventable vision loss in working-age adults. The objective of this Special Issue is to highlight the existing evidence regarding the relationship between oxidative stress and low-grade chronic inflammation induced by hyperglycemia with the development and progression of diabetic retinopathy, with an emphasis on the importance of early diagnosis and the use of antioxidant and anti-inflammatory approaches to prevent or delay the harmful effects of diabetes on retinal tissue.
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Keywords
- Aging
- Angiogenesis
- antioxidant
- Antioxidants
- Apoptosis
- aqueous humor
- ascorbic acid
- astaxanthin
- biomarkers
- biomarkers of diabetic retinopathy
- blood-retinal barrier
- carotenoid
- Cinnamomi Ramulus
- CPA4-1
- cyclooxygenase
- Cytochrome P450
- db/db mice
- Diabetes Mellitus
- diabetic retinopathy
- diabetic retinopathy (DR)
- docosahexaenoic acid (DHA)
- Eicosanoids
- eicosapentaenoic acid (EPA)
- epiretinal membrane
- extracellular vesicles
- fenofibrate
- free radicals
- GLP-1
- glycation
- glyoxalase
- HDAC6
- high-mobility group box 1 (HMGB1)
- human retina
- hyperglycemia
- Inflammation
- inflammatory pathways
- internal limiting membrane
- lipoxygenase
- macular hole
- medicine
- metabolic memory
- miRNA
- Mitochondria
- n/a
- novel therapies
- Nrf2
- occludin
- Oxidative Stress
- Paeoniae Radix
- photoreceptor
- photoreceptor cells
- PI3K
- proliferative diabetic retinopathy
- Reactive Oxygen Species
- redox
- Retinal disease
- retinal endothelial cell senescence
- retinal endothelial cells
- retinal pigment epithelium
- superoxide dismutase
- tear film
- thioredoxin
- tubastatin A
- Vitamin D
- vitreoretinal surgery
- vitreous humor
Links
DOI: 10.3390/books978-3-0365-0449-0Editions